Nickan Research Institute Immunopathologia Persa 2423-8015 4 1 2018 01 01 The role of microRNAs in human cancers e05 10.15171/ipp.2018.05 EN Mohammad-Reza Mahmoudian-Sani Ameneh Mehri-Ghahfarrokhi Ali Shojaeian Majid Asadi-Samani Tahra Luther Journal Article 10.15171/ipp.2018.05 2017 06 15 2017 08 20 MicroRNAs consist of 18 to 25 non-coding ribonucleic acids (RNA) that can act as oncogenes or tumor suppressors and in which mutations can lead to cancer. The identification of microRNAs and their target molecules has created a new horizon for studies of causes of cancer. MicroRNAs can be used as potential biological markers in diagnosis, prediction and treatment of cancers. This review article presents findings to explain microRNA’s function in human cancers.