Nickan Research Institute Immunopathologia Persa 2423-8015 11 1 2025 01 01 Deciphering gender disparities in laboratory biomarkers among deceased COVID-19 patients in Erbil city-Iraq: A retrospective study e40636 e40636 10.34172/ipp.2025.40636 EN Shukur Wasman Smail https://orcid.org/0000-0002-1915-5681 Aziz Muzafar Jaafar https://orcid.org/0000-0003-4522-8861 Mariwan Fathalla Abdalfatah https://orcid.org/0009-0009-6922-2422 Zhikal Omar Khudhur https://orcid.org/0000-0003-0687-1416 Abdullah Mahmood Abdullah https://orcid.org/0009-0005-0165-4238 Hijrat Zozk Abdulqadir https://orcid.org/0009-0002-8231-3598 Banoo Kamaran Ibraheem https://orcid.org/0009-0008-5359-1787 Avan Najmadeen Ahmad https://orcid.org/0009-0006-8574-7059 Dastan Abdullah Mohammed https://orcid.org/0009-0009-2249-536X Harem Khdir Awla https://orcid.org/0000-0003-1725-1730 Journal Article 10.34172/ipp.2025.40636 2024 03 08 2024 06 20 Introduction: SARS-CoV-2 was a new strain of the Coronaviridae family. It caused the coronavirus disease in December 2019 that first arose in Wuhan, China, and it developed into a worldwide health issue. COVID-19 gives rise to a wide range of symptoms which can range from having no symptoms to having extensive fatal pneumonia. Objectives: The purpose of the study was to figure out how infecting the virus could influence and impact the various laboratory biomarkers among dead male and female patients. Patients and Methods: The data and statistics were obtained from the dead patients of West Emergency Hospital and the data was investigated directly. The investigation was conducted from June 1st to November 1st, 2020. Epidemiological, clinical as well as lab data of approximately 659 dead cases of SARS-CoV-2 infected individuals were examined in that period. A real-time polymerase chain reaction (RT-PCR) technique was applied to confirm infecting of SARS-CoV-2. The deceased cases were categorized into 2 fractions, which were a male and female group. The male group had 407 individuals and the female group had 252 individuals. Results: This study revealed that the male cases had lower lymphocyte and platelet counts than females but substantially higher levels of urea and creatinine, also the male cases were older compared to the female cases. However, D-dimer and C-reactive protein (CRP ) levels did not indicate any notable differences between the two groups. Conclusion: The study showed a gender-situated differences in the laboratory biomarkers of dead COVID-19 cases.