Nickan Research Institute Immunopathologia Persa 2423-8015 11 1 2025 01 01 An infant with significant elevation of alanine aminotransferase and elevated serum creatinine: autoimmune hepatitis or not? e31340 e31340 10.34172/ipp.2022.31340 EN Mitra Ahmadi https://orcid.org/0000-0001-8215-9784 Hazhir Javaherizadeh https://orcid.org/0000-0001-7898-4589 Seyed Mohsen Dehghani https://orcid.org/0000-0001-5930-0110 Parisa Amoori https://orcid.org/0000-0002-4638-7920 Marjaneh Khalighi https://orcid.org/0000-0002-4773-3469 Journal Article 10.34172/ipp.2022.31340 2021 12 20 2022 02 10 A one-year-old boy with significantly elevated aminotransferase elevated creatinine and hepatomegaly was admitted to our hospital. Autoimmune hepatitis may have different presentations. Autoimmune hepatitis associated with a rise of blood urea nitrogen and creatinine level was not reported. We report this case with the probable diagnosis of autoimmune hepatitis with elevated blood urea nitrogen and serum creatinine.