Nickan Research Institute Immunopathologia Persa 2423-8015 2 1 2016 01 01 Introduction to chemical construction of immunotoxins and their applications in the treatment of diseases e02 EN Seyed Seifollah Beladi-Mousavi Khadije Hajibabaei Azam Hamledari Mohammad-Reza Tamadon Mohammad-Reza Ardalan Journal Article 2015 11 28 2015 12 26 Immunotoxins are mostly contain a monoclonal antibody part linked to a toxin, generally of bacterial or plant origin. The antibody gives specificity (ability to identify and react with the target), while the toxin gives cytotoxicity (ability to kill the target). In this paper, we will explain about the different parts of immunotoxins, linkage methods of the antibody to the toxin and their application in treatment of cancer and other diseases. This review will help physicians better inform patients about the potential benefits of these experimental treatments.