Nickan Research Institute Immunopathologia Persa 2423-8015 2 2 2016 07 01 Antioxidant supplements and cancer e14 EN Forouz Rastegari Mahmoud Rafieian-Kopaei Journal Article 2016 03 09 2016 03 26 Reactive oxygen species (ROS) can cause cancers. Owing to the causal role of ROS in raising cancers and the fact that different antioxidant promoters are considered tumor inhibitors, so far, epidemiological surveys show that an appropriate consumption of antioxidant-rich foods and supplements is inversely associated to cancer risk. However, some clinical trials with antioxidants do not support this idea. This paper will review the research conducted on the associations between antioxidant supplements consumption and cancers risk, especially on breast, prostate, lung and skin cancers.