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Submitted: 28 Dec 2024
Revision: 09 Mar 2025
Accepted: 10 Mar 2025
ePublished: 15 Mar 2025
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Immunopathol Persa. 2025;11(2): e43842.
doi: 10.34172/ipp.2025.43842
  Abstract View: 38
  PDF Download: 21

Original

Factor structure and measurement invariance by gender of the GHQ12 scale among parents of children with cancer

Asmaa Marrakchi 1,2 ORCID logo, Miloud Chakit 1* ORCID logo, Majdouline Obtel 3 ORCID logo, Fatima Ouasmani 2 ORCID logo, Meryem Qouhafa 1 ORCID logo, Naoual Elmorabit 2, Maria El Kababri 3,4 ORCID logo, Aboubaker El Hessni 1 ORCID logo, Abdelhalem Mesfioui 1 ORCID logo

1 Biology and Health Laboratory, Department of Biology, Ibn Tofail University, Kenitra, Morocco
2 Higher Institute of Nursing Professions and Technics of Health (ISPITS) - Ministry of Health and Social Welfare. Rabat, Morocco
3 Mohammed V University in Rabat, Faculty of Medicine and Pharmacy, Department of Public Health, Rabat, Morocco
4 Pediatric Hematology and Oncology Center, Children Hospital of Rabat, Rabat, Morocco
*Corresponding Author: Miloud Chakit, Email: miloud.chakit@uit.ac.ma

Abstract

Introduction: Although widely used, the General Health Questionnaire-12 (GHQ-12) has a model structure that remains open to debate. Initially conceived as unidimensional in earlier studies; however, numerous other research studies have proposed a multidimensional of GHQ-12.

Objectives: To assess the factor structure, internal reliability and invariance measure of a Moroccan GHQ-12 in a population of parents of children treated for cancer.

Patients and Methods: A total of 232 participants performed the Moroccan GHQ-12. The data obtained were subjected to exploratory factor analysis (EFA) to determine the potential factor structure of the scale of GHQ-12. Confirmatory factor analysis (CFA) models from previous studies are conducted for model fitting.

Results: The three-factor model was selected for its characteristics to best capture psychological distress (χ2 / dF=2.29, CFI=0.92, RMSEA=0.074) obtained by EFA. The reliability and construct validity of this model were satisfactory. The CFAs supported the configurational, scalar and metric invariances of this model.

Conclusion: The study validated the use of the scale of GHQ-12 in the assessment of psychological distress in parents of children with cancer, while proposing a three-factor model adapted to the Moroccan context which would enable targeted preventive interventions to be put in place.


Citation: Marrakchi A, Chakit M, Obtel M, Ouasmani F, Qouhafa M, Elmorabit N, El Kababri M, El Hessni A, Mesfioui A. Factor structure and measurement invariance by gender of the GHQ12 scale among parents of children with cancer. Immunopathol Persa. 2025;11(2):e43842. DOI:10.34172/ipp.2025.43842.
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