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Submitted: 08 May 2024
Accepted: 27 Sep 2024
ePublished: 26 Nov 2024
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Immunopathol Persa. Inpress.
doi: 10.34172/ipp.2025.40664
  Abstract View: 37

Original

Comparative study of gamma knife treatment between patients with metastasis and meningioma using the efficiency index

Marwa Ghanim Naish 1 ORCID logo, Taghreed Al-Sudani 2 ORCID logo, Safa Sami Hassan 3 ORCID logo, Nabaa Mohammed Alazawy 4* ORCID logo

1 Department of Radiology and Ultrasound, College of Medical and Health Technologies, Sawa University, Almuthana, Iraq
2 Medical Physics Unit, Physiology Department, College of Medicine, Baghdad University, Baghdad, Iraq
3 Department of Science, College of Basic Education, Mustansiriyah University, Baghdad, Iraq
4 Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
*Corresponding Author: Nabaa Mohammed Alazawy, Email: P126469@siswa.ukm.edu.my

Abstract

Introduction: In recent years, there have been significant advancements in medical technology that have substantially improved the efficacy of brain tumor therapy.

Objectives: To examine the efficacy of gamma knife in treating meningioma and metastatic brain cancer, using the efficiency index as a measure.

Patients and Methods: A total of 50 individuals were treated in a retrospective study with convenience sampling technique for meningioma and metastatic brain tumors. The neurosurgeon recommended an individualized dose based on the unique attributes of the tumor, including its dimensions and classification. The investigation used the Icon iteration of the gamma knife.

Results: Meningioma brain tumors had a much greater magnitude than metastatic malignancies in general. The results showed significant disparities between the two tumor types for treatment duration, extent of coverage, gradient index (GI), Paddick conformity index (PCI), and efficiency index (ƞ50%). Metastatic tumors had greater selectivity characteristics compared to meningioma tumors, with improved coverage, GI, PCI, treatment duration, and roughly 50%. The regression analysis revealed many noteworthy results about meningiomas and metastatic tumors. Significantly, there was a robust negative connection of 50% seen among the efficiency score, tumor size, coverage, PCI, and treatment duration. An association existed between the various forms of cancer and their corresponding degrees of selectivity, efficiency, and GI.

Conclusion: This research shows that the assessment criteria for meningioma are superior than those for metastases. Paddick’s efficiency index provides a very accurate prediction of the efficiency of meningioma, exceeding the predictive capabilities of metastasis.


Citation: Ghanim Naish M, Al-Sudani T, Hassan SS, Alazawy NM. Comparative study of gamma knife treatment between patients with metastasis and meningioma using the efficiency index. Immunopathol Persa. 2025;x(x):e40664. DOI:10.34172/ipp.2025.40664.
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