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Submitted: 01 May 2022
Accepted: 14 Jun 2022
ePublished: 24 Jun 2022
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Immunopathol Persa. 2024;10(1): e33402.
doi: 10.34172/ipp.2022.33402
  Abstract View: 968
  PDF Download: 176

Original

The positive association between various demographic characteristics and peak expiratory flow in employees of Zanjan university of medical sciences

Samad Ghodrati 1 ORCID logo, Jafar Kiasatfar 2, Negin Parsamanesh 3 ORCID logo, Shohreh Alian Samakkhah 4, Masoud Asadi-Khiavi 5,6 ORCID logo, Aiyoub Pezeshgi 1,3* ORCID logo

1 Department of Internal Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
2 Department of Internal Medicine, School of Medicine, West Azarbaijan University of Medical Sciences, Urmia, Iran
3 Zanjan Metabolic Diseases Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
4 Department of Food Hygiene, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies (AUSMT), Amol, Iran
5 Zanjan Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
6 Department of Pharmacotherapy, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran
*Corresponding Author: Aiyoub Pezeshgi, Email: dr.a.pezeshki@gmail.com, , Email: 50ayoub@zums.ac.ir

Abstract

Introduction: Peak expiratory flow (PEF) is a reliable criterion for assessing respiratory capacity, and has a wide range of clinical application as a marker of asthma control. However, its wide variability undermines its efficacy.

Objectives: This study was designed to evaluate PEF changes in staff of Zanjan University of Medical Sciences.

Patients and Methods: Four hundred employees of this university participated in this cross-sectional study. Their PEF values were measured using peak flow meter in the morning at 8 AM and in the afternoon at 2 PM by three times for each individual, and then the highest amount of PEF was recorded about for measurement.

Results: Obviously, PEF values were higher in the afternoon (43865 L/min) in comparison to the morning measurements (404.60 L/min) by paired t test (P<0.001). In addition, mean of PEF in the males was higher than the females in the morning (469.77 L/min, versus 355.94 L/min; independent t test, P<0.001), and also PEF mean of the morning and afternoon was higher in the males than females (404.6 L/min, versus 338.65 L/min, independent t test, P<0.001). Additionally, the variability level in the males and females was 8.39±6 and 8.47±4 L/min, respectively. There was a high correlation between the level of PEF variability and height (5.1). Meanwhile, a moderate correlation between PEF level and body mass index (BMI) was detected (1.47). There was not any correlation between the level of PEF and age.

Conclusion: Based on our findings, PEF inter-individual variability depends on age, gender height, and BMI however, it is worthwhile that this PEF inter-individual variability to be measured just until 4 PM. All these variables were obtained under the range of 20%; however, relying on references, the variability of 20% is considered as normal.


Citation: Ghodrati S, Kiasatfar J, Parsamanesh N, Alian Samakkhah S, Asadi-Khiavi M, Pezeshgi A. The positive association between various demographic characteristics and peak expiratory flow in employees of Zanjan university of medical sciences. Immunopathol Persa. 2024;10(1):e33402. DOI:10.34172/ ipp.2022.33402.
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