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Submitted: 01 Jan 2022
Accepted: 28 Apr 2022
ePublished: 28 May 2022
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Immunopathol Persa. Inpress.
doi: 10.34172/ipp.2022.31350
  Abstract View: 619

Original

Consistency analysis of ultrasound-guided fine-needle aspiration and histopathology results in thyroid nodules

Amir Bahrami 1 ORCID logo, Soheila Valizadeh 1 ORCID logo, Nasser Aghamohammadzadeh 1 ORCID logo, Farzad Najafipour 1 ORCID logo, Monireh Halimi 2 ORCID logo, Reza Javad-Rashid 3 ORCID logo, Javad Jalili 4 ORCID logo, Jalil Houshyar 1* ORCID logo

1 Endocrine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2 Department of Pathology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
3 Radiology Department, Medical Radiation Sciences Research Group, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
4 Radiology Department, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: *Correspondence to Jalil Houshyar, Email: hoshyarj2@gmail.com, , Email: houshyar@tbzmed.ac.ir

Abstract

Introduction: Thyroid nodules are considered as a frequent clinical problem. The great majority of thyroid nodules are benign; however malignancy probability is predicted to be 5-10%. The inconsistency between ultrasonography and fine-needle aspiration (FNA) findings is one of important problems in management of thyroid nodules.

Objectives: This study was designed to investigate the consistency of ultrasonography, FNA and histopathology findings in thyroid nodules.

Patients and Methods: In this descriptive study, 93 patients who were candidate for thyroid surgery were included. Data on ultrasound-guided fine-needle aspiration of the thyroid and histopathologic results before and after surgery were considered. The Cramér’s V and Fisher’s exact tests were conducted for this study.

Results: In patients whose ultrasound (US) results were low-suspicious, we observed a significant correlation between FNA and pathology results (Cramér’s V = 0.574, P = 0.037). However, relationship between FNA and pathology was not accessible among patients whose ultrasonography results were intermediate suspicious or high-suspicious due to insufficient number of samples.

Conclusion: In our study, a significant correlation was observed between FNA and pathology results in low-suspicious nodules.


Citation: Bahrami A, Valizadeh S, Aghamohammadzadeh N, Najafipour F, Halimi M, Javad-Rashid R, Jalili J, Houshyar J. Consistency analysis of ultrasound-guided fine-needle aspiration and histopathology results in thyroid nodules. Immunopathol Persa. 2022;x(x):e31350. DOI:10.34172/ ipp.2022.31350.
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