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Epidemiology and Prevention
An infant with significant elevation of alanine aminotransferase and elevated serum creatinine: autoimmune hepatitis or not?
Mitra Ahmadi
1,2 
, Hazhir Javaherizadeh
1,2* , Seyed Mohsen Dehghani
3 , Parisa Amoori
4 , Marjaneh Khalighi
2 1 Alimentary Tract Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Department of Pediatric Gastroenterology, Abuzar Children’s Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3 Gastroenterohepatology Research Center, Nemazee Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
4 Department of Pediatric Nephrology, Abuzar Children’s Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Abstract
A one-year-old boy with significantly elevated aminotransferase elevated creatinine and hepatomegaly was admitted to our hospital. Autoimmune hepatitis may have different presentations. Autoimmune hepatitis associated with a rise of blood urea nitrogen and creatinine level was not reported. We report this case with the probable diagnosis of autoimmune hepatitis with elevated blood urea nitrogen and serum creatinine.
Citation: Ahmadi M, Javaherizadeh H, Dehghani SM, Amoori P, Khalighi M. An infant with significant elevation of alanine aminotransferase and elevated serum creatinine: autoimmune hepatitis or not? Immunopathol Persa. 2025;11(1):e31340. DOI:10.34172/ipp.2022.31340.