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Submitted: 08 Sep 2020
Accepted: 20 Nov 2021
ePublished: 18 Sep 2022
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Immunopathol Persa. 2023;9(2): 15220.
doi: 10.34172/ipp.2023.15220

Scopus ID: 85164619806
  Abstract View: 587
  PDF Download: 493

Clinical Trial

The effect of a 10-week aerobic exercise on cardiac function among overweight female breast cancer survivors; a randomized clinical trial

Mohammadreza Khosravi Farsani 1,2* ORCID logo, Mahnaz Sourani 3 ORCID logo

1 Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Cancer Prevention Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
3 Department of Physical Education, Shahed University, Tehran, Iran
*Corresponding Author: Mohammadreza Khosravi Farsani, Email: Khosravifarsani@med.mui.ac.ir

Abstract

Introduction: Breast cancer is the most common and deadliest cancer among women.

Objectives: The aim of this study was to evaluate the effect of 10-week aerobic exercise on cardiac function among overweight female breast cancer survivors.

Patients and Methods: This triple-blinded randomized clinical trial was carried out among 25 overweight female breast cancer survivors (age range; 30-55 years). The aerobic exercise training protocol was performed for 10 weeks with an intensity of 40 to 75% of maximal heart rate. Anthropometric parameters and body composition of patients were measured (pre-test/post-test design). Echocardiography was used to determine the ejection fraction and pulmonary artery pressure of the patients too.

Results: There was no significant difference between anthropometric parameters and body composition of patients in the control and exercise groups. Additionally, there was a significant difference in the ejection fraction (P=0.001), PAP (P = 0.025) and VO2max between patients of control and exercise groups (P=0.001).

Conclusion: A 10-week aerobic exercise leads to an increase in the levels of VO2max, ejection fraction and pulmonary arterial pressure.

Trial Registration: Registration of trial protocol has been approved by Iranian Registry of Clinical Trials (identifier: IRCT20190218042745N1, https://www.irct.ir/trial/37684, ethical code; IR.MUI.REC.1396.2.082).


Citation: Khosravi Farsani M, Sourani M. The effect of a 10-week aerobic exercise on cardiac function among overweight female breast cancer survivors; a randomized clinical trial. Immunopathol Persa. 2023;9(2):e15220. doi: 10.34172/ ipp.2023.15220.
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