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Submitted: 09 Jun 2020
Accepted: 18 Sep 2020
ePublished: 08 Nov 2020
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Immunopathol Persa. Inpress.
doi: 10.34172/ipp.2022.12189
  Abstract View: 496

Original Article

Allergy status in children with adenoid hypertrophy with and without serous otitis media

Jalil Koohpayeh Zadeh 1, Babak Ghalebaghi 2 ORCID logo, Fatemeh Dehghani Firouzabadi 2* ORCID logo, Mohammad Dehghani Firouzabadi 2, Farzad Mohseni 3 ORCID logo, Maryam Biglari Abhari 4 ORCID logo, Reza Salehi 5 ORCID logo, Gholamreza Bayazian 6* ORCID logo

1 Preventive Medicine and Public Health Research Center, Iran University of Medical Sciences, Tehran, Iran
2 ENT and Head and Neck Research Center and Department, the Five Senses Institute, Iran University of Medical Sciences, Tehran, Iran
3 Family medicine Department, Iran University of Medical Science, Tehran, Iran
4 Community medicine Department, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran
5 Anesthesiology Department, Ali Asghar Pediatric Hospital, Iran University of Medical Science, Tehran, Iran
6 Ali Asghar Clinical Research Development Unit (AACRDU), Iran University of Medical Science, Tehran, Iran
*Corresponding Authors: *Correspondence to Gholamreza Bayazian, Email; Bayazian.g@iums.ac.ir, gr_ bayazian@yahoo.com, and Fatemeh Dehghani, Firouzabadi, Email; , Email: fatemehdehghanifirouzabadi@ gmail.com; *Correspondence to Gholamreza Bayazian, Email;_ bayazian@yahoo.com, and Fatemeh Dehghani, Firouzabadi, Email; fatemehdehghanifirouzabadi@ gmail.com, Email: Bayazian.g@iums.ac.ir, gr

Abstract

Introduction: Serous otitis media (SOM) is one of the most common diseases of children which can lead to hearing loss and imbalance in many cases.

Objective: To evaluate the relationship between allergy status and SOM in children with adenoid hypertrophy and whether affected by age group.

Materials and Methods: This cross-sectional study was conducted on 103 children aged 1-15 years with grade III or IV adenoid hypertrophy (± SOM) who referred to ear, nose, and throat (ENT) clinic. Additionally, children were divided into two subgroups based on age category of below and above seven years. The allergy status in children with and without SOM was compared by measuring the total immunoglobulin E (IgE) level, serum eosinophil level and skin prick test (SPT).

Results: There was no difference in prevalence of mean absolute eosinophil count (127.3 versus 141.3 eosinophils/ µL, respectively) (P=0.63), mean total IgE level (68.2 versus 140 IU/L, respectively; P=0.119) and positive SPT results (23.5% versus 28.4%, respectively; P=0.551) between children with adenoid hypertrophy (± SOM).

Conclusion: It seems absolute eosinophil count, total IgE level and positive SPT results have no significant role in SOM of children with adenoid hypertrophy and maybe other factors are implicated in its occurrence.


Citation: Koohpayeh Zadeh J, Ghalebaghi B, Dehghani Firouzabadi F, Dehghani Firouzabadi M, Mohseni F, Biglari Abhari M, Salehi R, Bayazian G. Allergy status in children with adenoid hypertrophy with and without serous otitis media. Immunopathol Persa. 2021;7(2):e22. DOI:10.34172/ ipp.2021.22.
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