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Submitted: 10 Jun 2017
Accepted: 19 Aug 2017
ePublished: 05 Sep 2017
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Immunopathol Persa. 2018;4(1): e07.
doi: 10.15171/ipp.2018.07
  Abstract View: 1141
  PDF Download: 1764

Epidemiology and Prevention

MicroRNAs in nephrology; new concepts

Sepideh Hajian 1 *

1 Department of Nephrology, Ghazvin University of Medical Sciences, Qhazvin, Iran
Correspondence to Sepideh Hajian dr.sepide_hajian@yahoo.com

Abstract

MicroRNAs play an important role in kidney physiology and pathology.  In fact, targeting of abnormal miRNAs in patients is applicable for treatment of related disorders.  It means that, administration of antagomirs as miRNA inhibitors could modulate the effect of miRNAs. Therefore it has therapeutic effect, but there is not sufficient data on the safety of these antisense oligonucleotide inhibitors. However, more studies in animal models and more clinical researches in this field are necessary. 
Keywords: MicroRNA, immunoglobulin A nephropathy, chronic kidney disease
Citation: Hajian S. MicroRNAs in nephrology; new concepts Immunopathol Persa. 2018;4(1):e07. doi: 10.15171/ipp.2018.07
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