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Submitted: 02 Jul 2019
Accepted: 30 Nov 2019
ePublished: 15 Feb 2020
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Immunopathol Persa. 2020;6(2): e14.
doi: 10.34172/ipp.2020.14
  Abstract View: 305
  PDF Download: 149

Case Report

Rapidly progressive fatal orbito-cerebral mucormycosis in an immunocompetent patient following entry of an insect into his eye; a case report and literature review

Saleh Mohebbi 1 ORCID logo, Mohammad Mahdi Salem 1, Hesam Eskandarzadeh 1, Ayda Sanaei 1 * ORCID logo, Mina Jamali 1

1 Department and Research Center for Otorhinolaryngology and Head & Neck Surgery, Hazrat-e Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
*Correspondence to Ayda Sanaei, Email: dr_aydasanaei@yahoo.com

Abstract

Mucormycosis, an uncommon and rapidly progressive fungal infection, is mainly seen in immunocompromised patients. However, immunocompetent individuals can also be infected. Here, we present a rapidly progressive orbito-cerebral mucormycosis in an immunocompetent patient, who had a history of entry of an insect into his eye. We report an immunocompetent patient, who had a history of entry of an insect into his eye, presented with left eye panophthalmitis, cellulitis and loss of vision. He underwent orbital exenteration. Then, mucormycosis was diagnosed and amphotericin B was initiated. Left cavernous sinus and internal carotid artery involvement were found in brain magnetic resonance imaging (MRI) and cerebrovascular accident (CVA) was diagnosed. Surgical debridement of necrotic tissue was performed, and postoperatively, our patient died following CVA. Mucormycosis, as a fatal fungal infection, requires early diagnosis, appropriate early surgical and rapid antifungal management so that successful outcome can be achieved.
Keywords: Mucormycosis, Immunocompetent, Cerebrovascular accident
Citation: Eskandarzadeh H, sanaei A, Mohebbi S, Salem MM, Jamali M. Rapidly progressive fatal orbito-cerebral mucormycosis in an immunocompetent patient following entry of an insect into his eye; a case report and literature review. Immunopathol Persa. 2019;5(2):exx. DOI:10.15171/ipp.2019. xx.
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