Logo-ipp
Submitted: 10 Apr 2019
Accepted: 20 Jun 2019
ePublished: 14 Jul 2019
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)

Immunopathol Persa. 2019;5(2): e16.
doi: 10.15171/ipp.2019.16
  Abstract View: 762
  PDF Download: 722

Mini-Review

Lung cancer risk and the inhibitors of angiotensinconverting enzyme: A mini-review of recent evidence

Masoumeh Asgharpour 1 ORCID logo, Mohammad Ebrahimi Kalan 2 ORCID logo, Seyed Hadi Mirhashemi 3, Amirhesam Alirezaei 4 * ORCID logo

1 Department of Nephrology, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran
2 Department of Epidemiology, Robert Stempel College of Public Health, Florida International University, Miami, FL, USA
3 Department of Surgery, Loghman hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4 Urology and Nephrology Research Center, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
*Correspondence to Amirhesam Alirezaei, Email: amirhesam124@gmail.com and Aalirezaei@sbmu.ac.ir

Abstract

Angiotensin-converting enzyme inhibitors (ACEIs) are among the most widely prescribed antihypertensive medications. They are indicated in the management of multiple chronic conditions including hypertension, diabetes mellitus and heart failure. ACEIs prevent angiotensin II (Ang II) production and bradykinin catabolism leading to vasodilation and reduction of arterial blood pressure. Recently, the role of the reninangiotensin system (RAS) inhibitors has become the subject of scrutiny in the treatment of cancer metastasis. The administration of ACEIs, however, has been described to be accompanying with carcinogenic effects.
Keywords: Cancer, Reninangiotensin system inhibitors, Antihypertensive medications, Renin-angiotensin system
Citation: Asgharpour M, Ebrahimi Kalan M, Mirhashemi SH, Alirezaei A. Lung cancer risk and the inhibitors of angiotensinconverting enzyme: A minireview of recent evidence. Immunopathol Persa. 2019;5(2):e16. DOI:10.15171/ ipp.2019.16.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 762

Your browser does not support the canvas element.


PDF Download: 722

Your browser does not support the canvas element.