Submitted: 13 Jul 2020
Accepted: 04 Oct 2020
ePublished: 01 Nov 2020
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Immunopathol Persa. 2021;7(2): e20.
doi: 10.34172/ipp.2021.20
  Abstract View: 173
  PDF Download: 127


Cachexia and anorexia in cancer; a systematic review

Ali Darakhshandeh 1 ORCID logo, Mahnaz Momenzadeh 2 * ORCID logo

1 Department of Internal Medicine, Hematology and Oncology Section, Isfahan University of Medical Sciences, Isfahan, Iran
2 Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
*Correspondence to Mahnaz Momenzadeh, Email: Mahnazmomenzadehf@gmail. com


The treatment strategy for cancer cachexia is based on the cachexia stage of the cancer and its phenotypes, therefore interventions and expected outcomes vary. In order for the patient to get the most out of the treatment, it should be done based on the mechanism of intervention and the quality of life of patients should be addressed, including aspects of rehabilitation and reduction of the patient’s suffering using a multidisciplinary team. Given the importance of the subject, the present study aims to investigate cachexia and anorexia in cancer. From the electronic databases, PubMed, Cochrane Library, Embase, Web of Sciences have been used to perform a systematic literature until 2020. Therefore, a software program (Endnote X8) has been utilized for managing electronic titles. Searches were performed with mesh terms. This review recommended that clinicians establish an interaction between cancer anorexia-cachexia syndrome (CACS) treatments and chronic pain treatments and choose the best treatment option.
Keywords: Cachexia, Anorexia, Cancer
Citation: Darakhshandeh A, Momenzadeh M. Cachexia and anorexia in cancer; a systematic review. Immunopathol Persa. 2021;7(2):e20. DOI:10.34172/ ipp.2021.20.
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