Immunopathol Persa. 2018;4(1):e05-.
doi: 10.15171/ipp.2018.05
  Abstract View: 468
  PDF Download: 740

Review

The role of microRNAs in human cancers

Mohammad-Reza Mahmoudian-Sani 1,2, Ameneh Mehri-Ghahfarrokhi 2, Ali Shojaeia 2, Majid Asadi-Samani 3 * , Tahra Luther 4

1 Department of Genetics and Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
2 Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran
3 Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran
4 Department of General Surgery, University of Michigan, Ann Arbor, Michigan, USA
*Correspondence to Majid Asadi-Samani Email: biology_2011@yahoo.com

Abstract

MicroRNAs consist of 18 to 25 non-coding ribonucleic acids (RNA) that can act as oncogenes or tumor suppressors and in which mutations can lead to cancer. The identification of microRNAs and their target molecules has created a new horizon for studies of causes of cancer. MicroRNAs can be used as potential biological markers in diagnosis, prediction and treatment of cancers. This review article presents findings to explain microRNA’s function in human cancers.
Citation: Mahmoudian- Sani MR, MehriGhahfarrokhi A, Shojaeian A, AsadiSamani M, Luther T.  The role of microRNAs in human cancers. Immunopathol Persa. 2018;4(1):e05. DOI: 10.15171/ipp.2018.05.
First name
 
Last name
 
Email address
 
Comments
 
Security code