Submitted: 27 Oct 2015
Accepted: 12 Dec 2015
First published online: 02 Jan 2016
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Immunopathol Persa. 2016;2(2):e17-.
  Abstract View: 242
  PDF Download: 254

Mini-Review

IgA vasculitis; from definition to classification of morphologic variables; an updated mini-review 

Hamid Nasri 1 *

1 Nickan Research Institute, Isfahan, Iran
Correspondence to Prof. Hamid Nasri Email: hamidnasri@med.mui.ac.ir

Abstract

All inflammatory modifications in the vessel wall are described as vasculitis. Pediatric vasculitis may existing with various clinical presentations. Immunoglobulin A vasculitis, is an immune complex vasculitis affecting small vessels with dominant IgA deposits. It is a small vessel vasculitis which can engage kidneys, gut, joints and skin, to varying degrees. Immunoglobulin A vasculitis, is the most common pediatric vasculitis usually recovers spontaneously, however, it is necessary to closely follow up of this disease because of the risk of kidney involvement, particularly in late-onset adult form of the disease. Both IgA nephropathy and IgA vasculitis are the same diseases, while IgA vasculitis is the systemic form of IgA nephropathy with presence of small vessel vasculitis. We suggest application of Oxford classification for IgA vasculitis and including of crescent as an additional morphologic variable in addition to MEST variables, which may have prognostic implication.
Citation: Nasri H. IgA vasculitis; from definition to classification of morphologic variables; an updated minireview. Immunopathol Persa. 2016;2(2):e17.
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